
产品货号:
Z34498
中文名称:
SYK Purified抗体
英文名称:
Anti-SYK Purified Antibody (Clone#SYK-01)
产品规格:
0.1mg(C100)
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-SYK Purified Antibody (Clone#SYK-01) |
指标别名 | spleen tyrosine kinase;SYK;Tyrosine protein kinase SYK |
克隆性 | Monoclonal |
检验物种 | human,rat,mouse |
应用范围 | IP,WB,IHC,ICC |
基因名称 | SYK |
克隆号 | SYK-01 |
抗体来源 | Mouse |
抗体类型 | IgG1 |
免疫原 | Recombinant fragment (aa 5-360) of human Syk.The antibody SYK-01 reacts with protein tyrosine kinase p72Syk (Syk;an intracellular antigen),which is required for the transduction of signals through the B cell antigen receptor (BCR) and the high affinity IgE receptor (FcepsilonRI). |
计算分子量 | 72kDa |
成分 | Phosphate buffered saline (PBS),pH7.4,15mM sodium azide |
纯化方式 | Purified by protein-A affinity chromatography. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | Store at 2~8℃.Do not freeze. |
背景资料 | Syk is a cytoplasmic protein tyrosine kinase that translocates to the plasma membrane upon B cell antigen receptor (BCR) or the high-affinity IgE receptor (FcepsilonRI) triggering,and phosphorylates downstream adaptor proteins,thereby providing docking sites for initiation of subsequent signaling pathways,such as calcium mobilization,cytoskeleton remodeling,or transcription of specific genes.Syk binds to the receptor assemblies through interactions of its pair of SH2 domains with ITAM motives of the receptor,which have been phosphorylated by Src-family kinases.These kinases also help to activate Syk by phosphorylation of its activation loop. |
Uniprot ID | P43405 |
基因名全称 | Spleen associated tyrosine kinase |
蛋白名全称 | Tyrosine-protein kinase SYK |
推荐稀释比 | Western blotting:1~2μg/mL. Immunohistochemistry (paraffin sections):5μg/mL;positive tissue:tonsil B cells. |
相关搜索:SYK Purified抗体,SYK Purified单抗,Anti-SYK Purified Antibody (Clone#SYK-01)